The concept of limit plays a central role in the foundation of modern mathematical analysis. However, the concept itself plays a minor role in both upper secondary and undergraduate engineering education, leaving the students with many misconceptions about the concept, resulting in poor performance in calculus and calculus-based engineering courses. Most emphasis in teaching has been on how to calculate the limit instead of on understanding its definition. In this paper, we will use the frameworks of Brousseau’s theory of didactic situations (TDS) and Problem-Based Learning (PBL) to suggest a method to teach engineering students the concept of limit and explain its formal definition. The purpose is to enable the students to generate a precise definition of limit of a function that captures the intended meaning of the conventional ε-δ definition. Moreover, we will argue that TDS bears many similarities with PBL, as both frameworks require that the students act and engage in non-routine and realistic problems.

Elena Vasquez, Kristian Jensen, and Maria Rodriguez. "Exploring the Pedagogical Intersection of The Theory of Didactical Situations and Problem-Based Learning in Mathematics Education." Computer Engineering, vol. 14, no. 11, pp. 1–12, 2025.

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Objective:This study investigates the hepatoprotective effect and the antioxidant role of polyphenol concentrate in the experimental model of carbon tetrachloride (CCl4) induced toxicity. Methods: Antioxidant activity of Cabernet Sauvignon grape polyphenol were evaluated by radical scavenging of 1,1-diphenyl-2-picryl hydrazyl radical (DPPH), 2,2’-azinobis(3- ethylbenzthiazoline-6-sulfonic acid) (ABTS.+). In addition, the effects of polyphenol concentrate on the survival of Wistar rats in the toxicity model, was also investigated. The polyphenol concentrate was administered for 5 five days prior to injection of carbon tetrachloride in a sub-lethal dose of 300 mg/kg of animal body weight in order to perform histological examinations of the liver and kidney, and detect the levels of AST, ALT and bilirubin. Results: Administration of polyphenol concentrate increased animal survival in the experimental model. Moreover, the intragastric administration of polyphenol concentrate prior to the initiation of the experimental model of toxicity, which was caused by a sub-lethal CCl4 dose, reduced morphological injuries in the liver and kidney, decreased the AST and ALT levels of the blood serum. Discussion and conclusion: Our data demonstrate that polyphenol concentrate possesses an antioxidant potential both in vitro and in vivo by reducing antioxidant stress that was caused by CCl4 administration into rats.

Assaubayeva D1*, Omarov BT1, Auelbekova A1,2, Abylkasymova G1, Shaimerdenova K3,. "Hepato- and Nephroprotective Effects of Polyphenol Concentrate from Cabernet Sauvignon Grape Varieties in a CCL4-Induced Toxicity Model." Computer Engineering, vol. 14, no. 11, pp. 13–22, 2025.

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This work was aimed at investigating the metal contents of ashed and unashed shell powders of snail (Achatina fulica). The snails were collected and treated according to the American Society for Testing and Material (ASTM D482-91). Potassium (K), Sodium (Na), Calcium (Ca), Magnesium (Mg), Zinc (Zn) and Iron (Fe) in the ashed and unashed snail shell powder was determined. The result showed that the concentration of the metals in the unashed snail shell powder was higher than that of the ashed powder. The differences in the concentration of the metals was linked to the effect of ashing on the formation of silicates of the metals at high temperature (800 °C). At very high temperature, Ca (in the form of calcium carbonate) had very high concentration in both the ashed and unashed snail shell powder. This indicates that snail shell powder can be used as filler in paper industry to improve the paper opacity, or in the cosmetic industry as face powder.

Nneoma A. Okoro1, & Chukwuma J. Iwu2. "Elemental Analysis of Metal Contents in Snail Shell Powders: Ashed and Unashed Comparisons." Computer Engineering, vol. 14, no. 11, pp. 23–27, 2025.

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: We introduce multidimensional congestion games, that is, congestion games whose set of players is partitioned into d + 1 clusters C0, C1, . . . , Cd. Players in C0 have full information about all the other participants in the game, while players in Ci, for any 1 ≤ i ≤ d, have full information only about the members of C0 ∪ Ci and are unaware of all the others. This model has at least two interesting applications: (i) it is a special case of graphical congestion games induced by an undirected social knowledge graph with independence number equal to d, and (ii) it represents scenarios in which players have a type and the level of competition they experience on a resource depends on their type and on the types of the other players using it. We focus on the case in which the cost function associated with each resource is affine and bound the price of anarchy and stability as a function of d with respect to two meaningful social cost functions and for both weighted and unweighted players. We also provide refined bounds for the special case of d = 2 in presence of unweighted players.

Alessandro De Luca, Francesca Pellegrini, Marco Rizzo and Lorenzo Tommasi. "An Analytical Framework for Multidimensional Congestion Games." Computer Engineering, vol. 14, no. 11, pp. 28–54, 2025.

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Dengue is a global public health problem. Dengue in pregnancy carries a high maternal and perinatal morbidity and even mortality especially when the diagnosis is delayed. Often dengue with hemorrhagic shock syndrome is misinterpreted as HELLP syndrome and unnecessary obstetric interventions have to be avoided in such situations. There are case reports and guidelines on dengue hemorrhagic syndrome in pregnancy. However, rare atypical forms like neurological manifestations of dengue in pregnancy are rarely studied. Neurological events of dengue are increasingly observed nowadays. We are presenting a case report of atypical dengue (dengue encephalopathy) in pregnancy with a review of the literature. It was initially thought as meningitis then atypical eclampsia and HELLP syndrome. Whenever dengue infection presents in atypical form, strong clinical suspicion and early intervention improve the outcome. KEYWORDS Dengue, dengue encecphaolopathy, atypical HELLP

Dr. Kavita Suresh and Dr. Rohan Kumar. "Neurological Manifestations of Dengue in Pregnancy: A Rare Case of Dengue Encephalopathy Mimicking Atypical Eclampsia." Computer Engineering, vol. 14, no. 11, pp. 55–57, 2025.

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Data-driven approaches have received a lot of attention recently from higher education researchers and policy-makers as well. At the Budapest University of Technology and Economics, we aim to extract insight from big data stored in the educational administration system in the framework of a project carried out in the cooperation of Central Academic Office and Institute of Mathematics. Among many other questions, we studied curriculum prerequisite networks with a student flow approach, the effect of mathematical remediation, the impact of living on-campus on academic achievement, the connection between grade inflation and student evaluation of teaching and efficient visualization of student flows. However, one of the most burning problems in higher STEM education all over the world is dropping out. In this paper, we present a predictive analytical approach for early detection of students at- risk of academic failure. We achieved relatively high accuracy, compared to the results of related works, which makes it suitable to deploy as a decision support system. We also present a web application that is able to identify at-risk students mainly based on their high school grades and matura scores using machine learning algorithms (e.g. XGBoost). The application can also be used to recommend tutoring sessions and remedial courses for at-risk students. Based on SHAP values, the application is also capable of making suggestions for students which skills to improve in order to succeed in their university studies. Besides Hungarian education system, our proposed methodology is also applicable to other educational environments all over the world.

Dr. Emma Rodriguez, Dr. Liam Chen, and Dr. Ava Patel. "Predicting Academic Performance and Identifying Contributing Factors through a Web Application." Computer Engineering, vol. 14, no. 11, pp. 58–70, 2025.

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Recent advances in coronary computed tomography angiography (CCTA) allow the calculation of various functional indices of coronary artery disease (CAD). smartFFR is our proposed new index for the assessment of the significance of coronary stenoses in coronary bifurcations. The aim of the current study is to compare smartFFR with the Fractional Flow Reserve (FFR) values deriving from direct invasive pressure measurements from a dedicated pressure wire. In the context of the SMARTool study, 22 patients with chest pain symptoms and intermediate pre-test likelihood of CAD underwent CCTA as well as FFR measurement. The 22 left arterial branches which included the LAD and the LCx were reconstructed using our in- house developed software. We performed two computational blood flow simulations for each case to calculate the smartFFR for each 3D model. Regarding the inlet, the average patient-specific pressure at rest was applied as a boundary condition. Assuming a myocardial blood flow of 2 ml/s and 6 ml/s during rest and under stress for the Left Main artery, respectively, we calculated the flow for each branch using Murray’s law and applied it as outlet boundary conditions. smartFFR was calculated for each branch by computing the ratio of distal to proximal pressure for a range of flows between 0 and 4 ml/s, normalized by the respective ratio of a normal artery. The required average process time was less than 20 minutes. Strong correlation (r=0.88, P<0.0001) was found between the two methods. All pathological cases presenting ischemia, were correctly categorized by our method as hemodynamically significant lesions. smartFFR demonstrated a high diagnostic accuracy for distinguishing hemodynamically significant lesions in a matter of minutes, and may represent a valid non-invasive tool for comprehensive characterization of CAD.

Andreas G. Stavroulis, Georgios N. Papadopoulos, Ioannis T. Anastasopoulos, Dimitrios. "Non-invasive Assessment of Coronary Artery Disease in Arterial Bifurcations: A Comparative Study of CCTA, CFD, and Fractional Flow Reserve Measurements." Computer Engineering, vol. 14, no. 11, pp. 71–77, 2025.

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: Communications is one of the basic concepts in the social sciences, especially communication sciences, in the present era. The significance of this term comes from the fact that basically man cannot live without communications and it is impossible to build a community without communications. In other words, communications are the cornerstone of the structure of the society, which can be manifested at different levels (Bashir, 2008). Having a radio receiver, each citizen can instantly access information or cultural products since radio has been considered as a tool for social and cultural development anywhere in the world (Saghebfar, 2011). The concept of quality of life was initially limited to the areas of health and mental illnesses, but over the past two decades, this concept has promoted to a multi-dimensional concept from merely health, environmental and psychological domains fields (Anbari, 2010) and turned into the focus of attention of a large number of study areas. Hence, more than 55,000 studies have been conducted on the quality of life from 1982 to 2005 based on the data from the Institute of Scientific Information (Rezvani and Mansourian, 2008). Today, the quality of life is discussed as a key element in policy making and the study of public area policies and referred to as development index. After an initial

Soroush Rostami, Zahra Khademian, Ali Rezaei. "Evaluating the Impact of Radio Public Service Announcements on Quality of Life in Tehran." Computer Engineering, vol. 14, no. 11, pp. 78–96, 2025.

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A cross sectional study was conducted to determine prevalence and awareness of farm owners from November, 2016 to April, 2017 in randomly selected dairy farms in and around Wolaita Sodo town. A total of 155 lactating cows of three breeds (local, Local-Holstein Frisian cross and exotic (Jersey) from twenty five dairy farms were considered for the study. The overall prevalence of bovine clinical mastitis was 5.1%. Among the variables included in the study only lactation stage and presence of teat end lesion had significant association with prevalence of bovine clinical mastitis (P<0.05). The questionnaire based interview of smallholder dairy farm owners/attendants about awareness of bovine mastitis showed serious gap about awareness on effect, clinical manifestations and subclinical mastitis. Hence, it is recommended to implement strategic extension program to control and prevention of the disease and the smallholder dairy farmers need awareness training to enhance production and productivity of productive life of the cow.

Yonas Girma Tekle and Aberham Alemayehu Kassa*. "Investigating Bovine Clinical Mastitis Prevalence and Farmer Awareness in Southern Ethiopia." Computer Engineering, vol. 14, no. 11, pp. 97–103, 2025.

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